The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA.

Direct sequencing of human mitochondrial tRNALysshows the absence of editing and the occurrence of six modified nucleotides (m1A9, m2G10, Psi27, Psi28 and hypermodified nucleotides at positions U34 and A37). This tRNA folds into the expected cloverleaf, as confirmed by structural probing with nuclea...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Helm, M, Brulé, H, Degoul, F, Cepanec, C, Leroux, J P, Giegé, R, Florentz, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9512533/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.7.1636
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!