The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA.

Direct sequencing of human mitochondrial tRNALysshows the absence of editing and the occurrence of six modified nucleotides (m1A9, m2G10, Psi27, Psi28 and hypermodified nucleotides at positions U34 and A37). This tRNA folds into the expected cloverleaf, as confirmed by structural probing with nuclea...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Helm, M, Brulé, H, Degoul, F, Cepanec, C, Leroux, J P, Giegé, R, Florentz, C
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1998
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9512533/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.7.1636
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