Non-discriminating and discriminating aspartyl-tRNA synthetases differ in the anticodon-binding domain

In most organisms, tRNA aminoacylation is ensured by 20 aminoacyl-tRNA synthetases (aaRSs). In eubacteria, however, synthetases can be duplicated as in Thermus thermophilus, which contains two distinct AspRSs. While AspRS-1 is specific, AspRS-2 is non-discriminating and aspartylates tRNA(Asp) and tR...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Charron, Christophe, Roy, Hervé, Blaise, Mickael, Giegé, Richard, Kern, Daniel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg148
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