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Non-discriminating and discriminating aspartyl-tRNA synthetases differ in the anticodon-binding domain
In most organisms, tRNA aminoacylation is ensured by 20 aminoacyl-tRNA synthetases (aaRSs). In eubacteria, however, synthetases can be duplicated as in Thermus thermophilus, which contains two distinct AspRSs. While AspRS-1 is specific, AspRS-2 is non-discriminating and aspartylates tRNA(Asp) and tR...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152893/ https://ncbi.nlm.nih.gov/pubmed/12660169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg148 |
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