Non-discriminating and discriminating aspartyl-tRNA synthetases differ in the anticodon-binding domain

In most organisms, tRNA aminoacylation is ensured by 20 aminoacyl-tRNA synthetases (aaRSs). In eubacteria, however, synthetases can be duplicated as in Thermus thermophilus, which contains two distinct AspRSs. While AspRS-1 is specific, AspRS-2 is non-discriminating and aspartylates tRNA(Asp) and tR...

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Bibliographic Details
Main Authors: Charron, Christophe, Roy, Hervé, Blaise, Mickael, Giegé, Richard, Kern, Daniel
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152893/
https://ncbi.nlm.nih.gov/pubmed/12660169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg148
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