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Role of dimerization in yeast aspartyl-tRNA synthetase and importance of the class II invariant proline.

Cytoplasmic aspartyl-tRNA synthetase (AspRS; EC 6.1.1.12) from yeast is, as are most class II synthetases, an alpha 2 dimer. The only invariant amino acid in signature motif 1 of this class is Pro-273; this residue is located at the dimer interface. To understand the role of Pro-273 in the conserved...

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Detalhes bibliográficos
Main Authors: Eriani, G, Cavarelli, J, Martin, F, Dirheimer, G, Moras, D, Gangloff, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47869/
https://ncbi.nlm.nih.gov/pubmed/8248175
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