Role of dimerization in yeast aspartyl-tRNA synthetase and importance of the class II invariant proline.
Cytoplasmic aspartyl-tRNA synthetase (AspRS; EC 6.1.1.12) from yeast is, as are most class II synthetases, an alpha 2 dimer. The only invariant amino acid in signature motif 1 of this class is Pro-273; this residue is located at the dimer interface. To understand the role of Pro-273 in the conserved...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10816 |
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