Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53.

Activation of the transcription factor NF-kappaB in response to a variety of stimuli is governed by the signal-induced proteolytic degradation of NF-kappaB inhibitor proteins, the IkappaBs. We have investigated the sequence requirements for signal-induced IkappaBalpha phosphorylation and proteolysis...

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Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Wulczyn, F G, Krappmann, D, Scheidereit, C
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 1998
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9512545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.7.1724
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