Signal-dependent degradation of IkappaBalpha is mediated by an inducible destruction box that can be transferred to NF-kappaB, bcl-3 or p53.

Activation of the transcription factor NF-kappaB in response to a variety of stimuli is governed by the signal-induced proteolytic degradation of NF-kappaB inhibitor proteins, the IkappaBs. We have investigated the sequence requirements for signal-induced IkappaBalpha phosphorylation and proteolysis...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Wulczyn, F G, Krappmann, D, Scheidereit, C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9512545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.7.1724
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!