Functional Correlation between a Novel Amino Acid Insertion at Codon 19 in the Protease of Human Immunodeficiency Virus Type 1 and Polymorphism in the p1/p6 Gag Cleavage Site in Drug Resistance and Replication Fitness

Population-based sequence analysis revealed the presence of a variant of human immunodeficiency virus type 1 (HIV-1) containing an insertion of amino acid Ile in the protease gene at codon 19 (19I) and amino acid substitutions in the protease at codons 21 (E21D) and 22 (A22V) along with multiple mut...

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Main Authors: Brann, Terrence W., Dewar, Robin L., Jiang, Min-Kan, Shah, Akram, Nagashima, Kunio, Metcalf, Julia A., Falloon, Judith, Lane, H. Clifford, Imamichi, Tomozumi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472590/
https://ncbi.nlm.nih.gov/pubmed/16731952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02212-05
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