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Low-frequency normal modes that describe allosteric transitions in biological nanomachines are robust to sequence variations
By representing the high-resolution crystal structures of a number of enzymes using the elastic network model, it has been shown that only a few low-frequency normal modes are needed to describe the large-scale domain movements that are triggered by ligand binding. Here we explore a link between the...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472502/ https://ncbi.nlm.nih.gov/pubmed/16682636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510426103 |
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