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The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria
NADH:ubiquinone oxidoreductase (complex I) is a major source of reactive oxygen species in mitochondria and a significant contributor to cellular oxidative stress. Here, we describe the kinetic and molecular mechanism of superoxide production by complex I isolated from bovine heart mitochondria and...
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Format: | Artigo |
Sprache: | Inglês |
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National Academy of Sciences
2006
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472492/ https://ncbi.nlm.nih.gov/pubmed/16682634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510977103 |
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