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Investigation of the mechanism of proton translocation by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria: does the enzyme operate by a Q-cycle mechanism?

Complex I (NADH:ubiquinone oxidoreductase) is the first enzyme of the membrane-bound electron transport chain in mitochondria. It conserves energy, from the reduction of ubiquinone by NADH, as a protonmotive force across the inner membrane, but the mechanism of energy transduction is not known. The...

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Библиографические подробности
Главные авторы: Sherwood, Steven, Hirst, Judy
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698589/
https://ncbi.nlm.nih.gov/pubmed/16895522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060766
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