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Reduction of Hydrophilic Ubiquinones by the Flavin in Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I) and Production of Reactive Oxygen Species

[Image: see text] NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria is a complicated, energy-transducing, membrane-bound enzyme that contains 45 different subunits, a non-covalently bound flavin mononucleotide, and eight iron−sulfur clusters. The mechanisms of NADH oxidation...

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Detalhes bibliográficos
Main Authors: King, Martin S., Sharpley, Mark S., Hirst, Judy
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2009
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651670/
https://ncbi.nlm.nih.gov/pubmed/19220002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802282h
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