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Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane

The relationship between protonmotive force and superoxide production by mitochondria is poorly understood. To address this issue, the rate of superoxide production from complex I of rat skeletal muscle mitochondria incubated under a variety of conditions was assessed. By far, the largest rate of su...

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Detalhes bibliográficos
Main Authors: Lambert, Adrian J., Brand, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133807/
https://ncbi.nlm.nih.gov/pubmed/15175007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040485
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