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Superoxide production by NADH:ubiquinone oxidoreductase (complex I) depends on the pH gradient across the mitochondrial inner membrane

The relationship between protonmotive force and superoxide production by mitochondria is poorly understood. To address this issue, the rate of superoxide production from complex I of rat skeletal muscle mitochondria incubated under a variety of conditions was assessed. By far, the largest rate of su...

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Bibliografske podrobnosti
Main Authors: Lambert, Adrian J., Brand, Martin D.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133807/
https://ncbi.nlm.nih.gov/pubmed/15175007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040485
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