Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

Exposure to inhaled allergens leads to increases in airway hyperresponsiveness (AHR) and inflammation, associated with increased levels of biologically active fragments derived from the complement C3 and C5 family of proteins. Further, complement activation during allergen challenge in sensitized an...

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Bibliografski detalji
Glavni autori: Taube, Christian, Thurman, Joshua M., Takeda, Katsuyuki, Joetham, Anthony, Miyahara, Nobuaki, Carroll, Michael C., Dakhama, Azzeddine, Giclas, Patricia C., Holers, V. Michael, Gelfand, Erwin W.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472433/
https://ncbi.nlm.nih.gov/pubmed/16702544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602357103
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