Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

Exposure to inhaled allergens leads to increases in airway hyperresponsiveness (AHR) and inflammation, associated with increased levels of biologically active fragments derived from the complement C3 and C5 family of proteins. Further, complement activation during allergen challenge in sensitized an...

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Detalhes bibliográficos
Main Authors: Taube, Christian, Thurman, Joshua M., Takeda, Katsuyuki, Joetham, Anthony, Miyahara, Nobuaki, Carroll, Michael C., Dakhama, Azzeddine, Giclas, Patricia C., Holers, V. Michael, Gelfand, Erwin W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472433/
https://ncbi.nlm.nih.gov/pubmed/16702544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602357103
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