Sodium Antimony Gluconate Induces Generation of Reactive Oxygen Species and Nitric Oxide via Phosphoinositide 3-Kinase and Mitogen-Activated Protein Kinase Activation in Leishmania donovani-Infected Macrophages

Pentavalent antimony complexes, such as sodium stibogluconate and sodium antimony gluconate (SAG), are still the first choice for chemotherapy against various forms of leishmaniasis, including visceral leishmaniasis, or kala-azar. Although the requirement of a somewhat functional immune system for t...

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Bibliografski detalji
Glavni autori: Mookerjee Basu, Jayati, Mookerjee, Ananda, Sen, Prosenjit, Bhaumik, Suniti, Sen, Pradip, Banerjee, Subha, Naskar, Ksudiram, Choudhuri, Soumitra K., Saha, Bhaskar, Raha, Sanghamitra, Roy, Syamal
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Mechanisms of Action: Physiological Effects
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472228/
https://ncbi.nlm.nih.gov/pubmed/16641451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1788-1797.2006
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