Sodium Antimony Gluconate Induces Generation of Reactive Oxygen Species and Nitric Oxide via Phosphoinositide 3-Kinase and Mitogen-Activated Protein Kinase Activation in Leishmania donovani-Infected Macrophages

Pentavalent antimony complexes, such as sodium stibogluconate and sodium antimony gluconate (SAG), are still the first choice for chemotherapy against various forms of leishmaniasis, including visceral leishmaniasis, or kala-azar. Although the requirement of a somewhat functional immune system for t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mookerjee Basu, Jayati, Mookerjee, Ananda, Sen, Prosenjit, Bhaumik, Suniti, Sen, Pradip, Banerjee, Subha, Naskar, Ksudiram, Choudhuri, Soumitra K., Saha, Bhaskar, Raha, Sanghamitra, Roy, Syamal
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Mechanisms of Action: Physiological Effects
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472228/
https://ncbi.nlm.nih.gov/pubmed/16641451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1788-1797.2006
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