Sodium Antimony Gluconate Induces Generation of Reactive Oxygen Species and Nitric Oxide via Phosphoinositide 3-Kinase and Mitogen-Activated Protein Kinase Activation in Leishmania donovani-Infected Macrophages

Pentavalent antimony complexes, such as sodium stibogluconate and sodium antimony gluconate (SAG), are still the first choice for chemotherapy against various forms of leishmaniasis, including visceral leishmaniasis, or kala-azar. Although the requirement of a somewhat functional immune system for t...

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Dades bibliogràfiques
Autors principals: Mookerjee Basu, Jayati, Mookerjee, Ananda, Sen, Prosenjit, Bhaumik, Suniti, Sen, Pradip, Banerjee, Subha, Naskar, Ksudiram, Choudhuri, Soumitra K., Saha, Bhaskar, Raha, Sanghamitra, Roy, Syamal
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Mechanisms of Action: Physiological Effects
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472228/
https://ncbi.nlm.nih.gov/pubmed/16641451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1788-1797.2006
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