Sodium Antimony Gluconate Induces Generation of Reactive Oxygen Species and Nitric Oxide via Phosphoinositide 3-Kinase and Mitogen-Activated Protein Kinase Activation in Leishmania donovani-Infected Macrophages

Pentavalent antimony complexes, such as sodium stibogluconate and sodium antimony gluconate (SAG), are still the first choice for chemotherapy against various forms of leishmaniasis, including visceral leishmaniasis, or kala-azar. Although the requirement of a somewhat functional immune system for t...

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Detalhes bibliográficos
Main Authors: Mookerjee Basu, Jayati, Mookerjee, Ananda, Sen, Prosenjit, Bhaumik, Suniti, Sen, Pradip, Banerjee, Subha, Naskar, Ksudiram, Choudhuri, Soumitra K., Saha, Bhaskar, Raha, Sanghamitra, Roy, Syamal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472228/
https://ncbi.nlm.nih.gov/pubmed/16641451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1788-1797.2006
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