Mice Develop Effective but Delayed Protective Immune Responses When Immunized as Neonates either Intranasally with Nonliving VP6/LT(R192G) or Orally with Live Rhesus Rotavirus Vaccine Candidates

Rotavirus vaccines are delivered early in life, when the immune system is immature. To determine the effects of immaturity on responses to candidate vaccines, neonatal (7 days old) and adult mice were immunized with single doses of either Escherichia coli-expressed rotavirus VP6 protein and the adju...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: VanCott, John L., Prada, Anne E., McNeal, Monica M., Stone, Susan C., Basu, Mitali, Huffer, Bert, Smiley, Kristi L., Shao, Mingyuan, Bean, Judy A., Clements, John D., Choi, Anthony H.-C., Ward, Richard L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2006
Pynciau:
Pathogenesis and Immunity
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472046/
https://ncbi.nlm.nih.gov/pubmed/16641286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.10.4949-4961.2006
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