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Functional Mapping of Protective Domains and Epitopes in the Rotavirus VP6 Protein

The purpose of this study was to determine which regions of the VP6 protein of the murine rotavirus strain EDIM are able to elicit protection against rotavirus shedding in the adult mouse model following intranasal (i.n.) immunization with fragments of VP6 and a subsequent oral EDIM challenge. In th...

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Autori principali: Choi, Anthony H. C., Basu, Mitali, McNeal, Monica M., Flint, Jason, VanCott, John L., Clements, John D., Ward, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC112438/
https://ncbi.nlm.nih.gov/pubmed/11090155
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