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Kinetics of Insulin Aggregation: Disentanglement of Amyloid Fibrillation from Large-Size Cluster Formation
Kinetics of human insulin aggregation has been studied at pH 1.6 and 60°C, when amyloid fibrils are formed. We developed a novel approach based on the analysis of scattered light intensity distribution, which allows distinguishing between small and large size aggregates. By this method, we observed...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Biophysical Society
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1471846/ https://ncbi.nlm.nih.gov/pubmed/16581839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.077636 |
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