Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

Topoisomerase I (TOP1)-mediated DNA damage induced by camptothecin (CPT) in the presence of active transcription has been studied using purified calf thymus TOP1 and T7 RNA polymerase. CPT-stabilized TOP1 cleavable complexes located on the template strand within the transcribed region were found to...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, J, Liu, L F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC147056/
https://ncbi.nlm.nih.gov/pubmed/9336444
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