Chargement en cours...

Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

Topoisomerase I (TOP1)-mediated DNA damage induced by camptothecin (CPT) in the presence of active transcription has been studied using purified calf thymus TOP1 and T7 RNA polymerase. CPT-stabilized TOP1 cleavable complexes located on the template strand within the transcribed region were found to...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wu, J, Liu, L F
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC147056/
https://ncbi.nlm.nih.gov/pubmed/9336444
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!