Interaction of endostatin with integrins implicated in angiogenesis

Endostatin, a fragment of collagen XVIII, is a potent antagonist of angiogenesis and inhibitor of tumor growth in mouse models. At present, the mechanism of action of endostatin is unknown. We show here that recombinantly produced human endostatin interacts with α(5)- and α(v)-integrins on the surfa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rehn, Marko, Veikkola, Tanja, Kukk-Valdre, Eola, Nakamura, Hitoshi, Ilmonen, Maritta, Lombardo, Christian R., Pihlajaniemi, Taina, Alitalo, Kari, Vuori, Kristiina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2001
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC14702/
https://ncbi.nlm.nih.gov/pubmed/11158588
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