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Replication of DNA templates containing 5-formyluracil, a major oxidative lesion of thymine in DNA.

5-Formyluracil (5-foU) is a major lesion of thymine produced in DNA by ionizing radiation and various chemical oxidants. To assess its biochemical effects on DNA replication, 22mer oligonucleotide templates containing an internal 5-foU at defined sites were synthesized by the phosphoramidite method...

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Udgivet i:Nucleic Acids Res
Principais autores: Zhang, Q M, Sugiyama, H, Miyabe, I, Matsuda, S, Saito, I, Yonei, S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147013/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9321644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.20.3969
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