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Selectin receptor–ligand bonds: Formation limited by shear rate and dissociation governed by the Bell model

We have studied the principles that govern the formation and dissociation of an adhesive bond between a cell moving in shear flow and a substrate and tested different theories of how force affects bond dissociation. Viscosity relates the kinematics of fluid movement (shear rate, units of time(−1)) t...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Chen, Shuqi, Springer, Timothy A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.3.950
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