Synthesis and hybridization properties of inverse oligonucleotides.

The synthesis of adenine and thymine cyclopentylethyl nucleosides is presented. This novel constrained monomeric building block is very difficult to incorporate into oligonucleotides. It was introduced in 13mer oligodeoxynucleotide sequences at a single position using H-phosphonate chemistry. Phosph...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Marangoni, M, Van Aerschot, A, Augustyns, P, Rozenski, J, Herdewijn, P
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9224602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.15.3034
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