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Synthesis and hybridization properties of inverse oligonucleotides.

The synthesis of adenine and thymine cyclopentylethyl nucleosides is presented. This novel constrained monomeric building block is very difficult to incorporate into oligonucleotides. It was introduced in 13mer oligodeoxynucleotide sequences at a single position using H-phosphonate chemistry. Phosph...

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Bibliografische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Marangoni, M, Van Aerschot, A, Augustyns, P, Rozenski, J, Herdewijn, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146838/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9224602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.15.3034
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