Synthesis and hybridization properties of inverse oligonucleotides.

The synthesis of adenine and thymine cyclopentylethyl nucleosides is presented. This novel constrained monomeric building block is very difficult to incorporate into oligonucleotides. It was introduced in 13mer oligodeoxynucleotide sequences at a single position using H-phosphonate chemistry. Phosph...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Marangoni, M, Van Aerschot, A, Augustyns, P, Rozenski, J, Herdewijn, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9224602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.15.3034
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