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Influence of the incorporation of (S)-9-(3,4-dihydroxybutyl)adenine on the enzymatic stability and base-pairing properties of oligodeoxynucleotides.

(S)-9-(3,4-dihydroxybutyl)adenine was used at several positions as nucleoside substitute in the synthesis of dimers and 13-mers. Therefore we used the phosporamidite and the H-phosphonate chemistry. The nuclease susceptibilities and the base-pairing properties of these oligomers have been evaluated.

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Augustyns, K, Van Aerschot, A, Van Schepdael, A, Urbanke, C, Herdewijn, P
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1991
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2041735/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.10.2587
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