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Synthesis and hybridization properties of inverse oligonucleotides.

The synthesis of adenine and thymine cyclopentylethyl nucleosides is presented. This novel constrained monomeric building block is very difficult to incorporate into oligonucleotides. It was introduced in 13mer oligodeoxynucleotide sequences at a single position using H-phosphonate chemistry. Phosph...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Marangoni, M, Van Aerschot, A, Augustyns, P, Rozenski, J, Herdewijn, P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC146838/
https://ncbi.nlm.nih.gov/pubmed/9224602
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