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Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB site.

Interleukin-6 (IL-6) is a multifunctional cytokine thought to be a key factor in post-menopausal osteoporosis, given its ability to induce osteoclast maturation and its down regulation by estrogens. We have previously shown that the effects of TNFalphaand estradiol on the human IL-6 promoter were de...

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Bibliografske podrobnosti
Main Authors: Galien, R, Garcia, T
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC146754/
https://ncbi.nlm.nih.gov/pubmed/9171095
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