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Induction of AIDS by simian immunodeficiency virus lacking NF-kappaB and SP1 binding elements.

Rhesus monkeys (Macaca mulatta) were infected with five strains of simian immunodeficiency virus (SIV) derived from SIVmac239 containing deletions (delta) or substitutions (subst) in NF-kappaB and Sp1 binding sites. We have shown previously that mutations in these regions still allow efficient SIVma...

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Bibliographic Details
Main Authors: Ilyinskii, P O, Simon, M A, Czajak, S C, Lackner, A A, Desrosiers, R C
Format: Artigo
Language:Inglês
Published: 1997
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191258/
https://ncbi.nlm.nih.gov/pubmed/9032318
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