Triple helix formation with purine-rich phosphorothioate-containing oligonucleotides covalently linked to an acridine derivative.

Purine-rich (GA)- and (GT)-containing oligophosphorothioates were investigated for their triplex-forming potential on a 23 bp DNA duplex target. In our system, GA-containing oligophosphorothioates (23mer GA-PS) were capable of triplex formation with binding affinities lower than (GA)-containing olig...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Lacoste, J, François, J C, Hélène, C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9115367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.10.1991
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