Triple helix formation with purine-rich phosphorothioate-containing oligonucleotides covalently linked to an acridine derivative.

Purine-rich (GA)- and (GT)-containing oligophosphorothioates were investigated for their triplex-forming potential on a 23 bp DNA duplex target. In our system, GA-containing oligophosphorothioates (23mer GA-PS) were capable of triplex formation with binding affinities lower than (GA)-containing olig...

Полное описание

Библиографические подробности

Опубликовано в::	Nucleic Acids Res
Главные авторы:	Lacoste, J, François, J C, Hélène, C
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 1997
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9115367/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.10.1991
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!