Evaluation of pyrimidine PNA binding to ssDNA targets from nonequilibrium melting experiments.

Slow kinetics of homopyrimidine PNA binding to single stranded DNA and RNA targets is manifested in significant hysteresis in thermal UV absorption experiments. We have compared temperatures of dissociation (Tdis) and reassociation (Tass) for triplexes formed by DNA and single or bis PNAs with K50 d...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Lesnik, E A, Risen, L M, Driver, D A, Griffith, M C, Sprankle, K, Freier, S M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016597/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.3.568
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