Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins.
The antitumor agent cis-diamminedichloroplatinum(II) (cisplatin) introduces cytotoxic DNA damage predominantly in the form of intrastrand crosslinks between adjacent purines. Binding assays using a series of duplex oligonucleotides containing a single 1,2 diguanyl intrastrand crosslink indicate that...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.3.491 |
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