Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins.

The antitumor agent cis-diamminedichloroplatinum(II) (cisplatin) introduces cytotoxic DNA damage predominantly in the form of intrastrand crosslinks between adjacent purines. Binding assays using a series of duplex oligonucleotides containing a single 1,2 diguanyl intrastrand crosslink indicate that...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Yamada, M, O'Regan, E, Brown, R, Karran, P
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1997
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146450/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9016586/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.3.491
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