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Neurosteroid administration and withdrawal alter GABA(A) receptor kinetics in CA1 hippocampus of female rats

Withdrawal from the GABA-modulatory steroid 3α-OH-5α-pregnan-20-one (3α,5α-THP) following exposure of female rats to the parent compound progesterone (P) produces a syndrome characterized by behavioural excitability in association with up-regulation of the α4 subunit of the GABA(A) receptor (GABAR)...

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Detalles Bibliográficos
Main Authors: Smith, Sheryl S, Gong, Qi Hua
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464432/
https://ncbi.nlm.nih.gov/pubmed/15705652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077297
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