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Neurosteroid administration and withdrawal alter GABA(A) receptor kinetics in CA1 hippocampus of female rats
Withdrawal from the GABA-modulatory steroid 3α-OH-5α-pregnan-20-one (3α,5α-THP) following exposure of female rats to the parent compound progesterone (P) produces a syndrome characterized by behavioural excitability in association with up-regulation of the α4 subunit of the GABA(A) receptor (GABAR)...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Science Inc
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464432/ https://ncbi.nlm.nih.gov/pubmed/15705652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077297 |
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