Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection

Primate tripartite motif 5α (TRIM5α) proteins mediate innate intracellular resistance to retroviruses. In humans, TRIM5 is located in a paralogous cluster that includes TRIM6, TRIM34, and TRIM22. Although TRIM6 and TRIM34 orthologs are found in other mammals, TRIM5 has to date been identified only i...

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Autori principali: Si, Zhihai, Vandegraaff, Nick, O’hUigin, Colm, Song, Byeongwoon, Yuan, Wen, Xu, Chen, Perron, Michel, Li, Xing, Marasco, Wayne A., Engelman, Alan, Dean, Michael, Sodroski, Joseph
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464360/
https://ncbi.nlm.nih.gov/pubmed/16648259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600771103
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