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Determinants of the Higher Order Association of the Restriction Factor TRIM5α and Other Tripartite Motif (TRIM) Proteins

Many tripartite motif (TRIM) proteins self-associate, forming dimers and higher order complexes. For example, dimers of TRIM5α, a host factor that restricts retrovirus infection, assemble into higher order arrays on the surface of the viral capsid, resulting in an increase in avidity. Here we show t...

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Detalhes bibliográficos
Main Authors: Li, Xing, Yeung, Darwin F., Fiegen, Ann M., Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151041/
https://ncbi.nlm.nih.gov/pubmed/21680743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.260406
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