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Human Tripartite Motif 5α Domains Responsible for Retrovirus Restriction Activity and Specificity
The tripartite motif 5α protein (TRIM5α) is one of several factors expressed by mammalian cells that inhibit retrovirus replication. Human TRIM5α (huTRIM5α) inhibits infection by N-tropic murine leukemia virus (N-MLV) but is inactive against human immunodeficiency virus type 1 (HIV-1). However, we s...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1168745/ https://ncbi.nlm.nih.gov/pubmed/15994791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8969-8978.2005 |
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