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An amino-terminal lysine residue of rat connexin40 that is required for spermine block
Spermine blocks connexin40 (Cx40) gap junctions, and two cytoplasmic amino-terminal domain glutamate residues are essential for this inhibitory activity. To further examine the molecular basis for block, we mutated a portion of a basic amino acid (HKH) motif on the Cx40 amino-terminal domain. Replac...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464307/ https://ncbi.nlm.nih.gov/pubmed/16284078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.097188 |
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