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Voltage-Dependent Blockade of Connexin40 Gap Junctions by Spermine

The effects of spermine and spermidine, endogenous polyamines that block many forms of ion channels, were investigated in homotypic connexin (Cx)-40 gap junctions expressed in N2A cells. Spermine blocked up to 95% of I(j) through homotypic Cx40 gap junctions in a concentration- and transjunctional v...

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Detalles Bibliográficos
Main Authors: Musa, Hassan, Veenstra, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302604/
https://ncbi.nlm.nih.gov/pubmed/12524276
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