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Voltage-Dependent Blockade of Connexin40 Gap Junctions by Spermine
The effects of spermine and spermidine, endogenous polyamines that block many forms of ion channels, were investigated in homotypic connexin (Cx)-40 gap junctions expressed in N2A cells. Spermine blocked up to 95% of I(j) through homotypic Cx40 gap junctions in a concentration- and transjunctional v...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Biophysical Society
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1302604/ https://ncbi.nlm.nih.gov/pubmed/12524276 |
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