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Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes
Pre-T cell receptor (preTCR)-derived signals mediate the transition of thymocytes from the CD4(−) CD8(−) double-negative (DN) to CD4(+) CD8(+) double-positive stage of T lymphocyte development. This progression, termed β-selection, is limited to thymocytes that have generated a functional TCR-β chai...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC14635/ https://ncbi.nlm.nih.gov/pubmed/11149941 |
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