SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis

BACKGROUND: SSeCKS is a major protein kinase C substrate with kinase scaffolding and metastasis-suppressor activity whose expression is severely downregulated in Src- and Ras-transformed fibroblast and epithelial cells and in human prostate, breast, and gastric cancers. We previously used NIH3T3 cel...

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Bibliographic Details
Main Authors: Liu, Yongzhong, Gao, Lingqiu, Gelman, Irwin H
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1463002/
https://ncbi.nlm.nih.gov/pubmed/16638134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-105
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