Control of Protein Kinase C Activity, Phorbol Ester-induced Cytoskeletal Remodeling, and Cell Survival Signals by the Scaffolding Protein SSeCKS/GRAVIN/AKAP12

The product of the SSeCKS/GRAVIN/AKAP12 gene (“SSeCKS”) is a major protein kinase (PK) C substrate that exhibits tumor- and metastasis-suppressing activity likely through its ability to scaffold multiple signaling mediators such as PKC, PKA, cyclins, calmodulin, and Src. Although SSeCKS and PKCα bin...

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Bibliografiske detaljer
Main Authors: Guo, Li-Wu, Gao, Lingqiu, Rothschild, Julian, Su, Bing, Gelman, Irwin H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207390/
https://ncbi.nlm.nih.gov/pubmed/21903576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258830
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