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Mapping genes within a YAC by computer-assisted interpretation of partial restriction digestions.

Partial restriction digestion is used to map restriction sites and the location of genes within yeast artificial chromosomes (YACs). Locus-specific probes are hybridised to the partially digested YAC DNA and the fragments to which they hybridise are compared with the pattern of partial digestion pro...

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Autors principals: Shields, D C, Butler, A, Mosurski, K R, Walsh, M T, Whitehead, A S
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC146272/
https://ncbi.nlm.nih.gov/pubmed/8948640
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