A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion or cell lethality.
Human chromosomal DNA contains many repeats which might provide opportunities for DNA repair. We have examined the consequences of a single double-strand break (DSB) within a 360-kb dispensable yeast artificial chromosome (YAC) containing human DNA (YAC12). An Alu-URA3-YZ sequence was targeted to se...
সংরক্ষণ করুন:
| প্রকাশিত: | Mol Cell Biol |
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| প্রধান লেখক: | , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
Taylor & Francis
1996
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4414 |
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