A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion or cell lethality.

Human chromosomal DNA contains many repeats which might provide opportunities for DNA repair. We have examined the consequences of a single double-strand break (DSB) within a 360-kb dispensable yeast artificial chromosome (YAC) containing human DNA (YAC12). An Alu-URA3-YZ sequence was targeted to se...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Bennett, C B, Westmoreland, T J, Snipe, J R, Resnick, M A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8754842/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.16.8.4414
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!