A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion or cell lethality.

類似資料

• SIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome
  著者:: Bennett, Craig B., 等
  出版事項: (2001)
• Meiotic double-strand breaks in yeast artificial chromosomes containing human DNA.
  著者:: Ira, G, 等
  出版事項: (1998)
• Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid.
  著者:: Bennett, C B, 等
  出版事項: (1993)
• Analysis of chromosome 21 yeast artificial chromosome (YAC) clones.
  著者:: Tassone, F, 等
  出版事項: (1992)
• Recombination during transformation as a source of chimeric mammalian artificial chromosomes in yeast (YACs).
  著者:: Larionov, V, 等
  出版事項: (1994)